Across TCGA patient cohorts, COLCA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,909 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible COLCA1-associated proteins across cancer lineages are BZW1, EIF4G1, and MAP3K4_S431. Each is linked with COLCA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both COLCA1-to-partner and partner-to-COLCA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COLCA1→partner) and Y-score (partner→COLCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BZW1 →	-0.324	-0.952	<.001	<.001	3	7
CCRCC	EIF4G1 →	-0.256	-0.747	<.001	<.001	3	5
GBM	MAP3K4_S431 →	-0.442	-0.996	<.001	<.001	3	5
HNSC	MAP4_S696 →	-0.619	-1.058	<.001	<.001	3	5
CCRCC	NRBF2_S113 →	-0.674	-0.909	<.001	<.001	3	5
PDAC	PLEC_S1284 →	-0.954	-1.005	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,909 associations by consensus.

Exploration

COLCA1 survival (RNA) · tumor vs normal (RNA) · all COLCA1 data types