COL9A3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL9A3 mutation is significantly associated with the RNA expression of many other genes, with 1,933 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL9A3-associated genes across cancer lineages are LINC02559, NF1P6, and CDRT15P7. Each is linked with COL9A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL9A3-to-partner and partner-to-COL9A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by COL9A3-low versus COL9A3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL9A3→partner) and Y-score (partner→COL9A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCLINC02559 →+0.964+4.505<.001.00933
CESCNF1P6 →+0.248+5.342<.001.00233
CESCCDRT15P7 →+0.058+4.669<.001.00733
SKCMMIR6731 →+0.327+1.958.001.00132
BRCAOR4V1P →+0.223+6.038<.001.00132
STADTTTY8 →+0.024+5.012<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,933 associations by consensus.

LINC02559 by COL9A3 expression — HNSC

Box plot of LINC02559 in COL9A3-low vs COL9A3-high samples in HNSC.

Explore this box plot interactively →

Exploration