COL9A3

Across TCGA patient cohorts, COL9A3 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL9A3-associated genes across cancer lineages are TFRC, IGFBP2, and Raptor. Each is linked with COL9A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL9A3-to-partner and partner-to-COL9A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by COL9A3-low versus COL9A3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL9A3→partner) and Y-score (partner→COL9A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TFRC →	+0.695	+3.321	.002	.009	3	2
SKCM	IGFBP2 →	-0.545	-3.000	.026	.034	3	2
LUAD	Raptor →	+0.191	+2.824	.043	.034	3	1
LUAD	VEGFR2 →	-0.414	-2.584	.009	.011	3	1
UCEC	EGFR →	-0.106	-1.321	.047	.029	3	1
UCEC	ERK2 →	+0.144	+1.700	.025	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

TFRC by COL9A3 expression — LUAD

Explore this box plot interactively →