COL9A3

Across TCGA cell cohorts, COL9A3 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL9A3-associated genes across cancer lineages are AICDA, LCE3D, and KRTAP4-12. Each is linked with COL9A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL9A3-to-partner and partner-to-COL9A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AICDA grouped by COL9A3-low versus COL9A3-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL9A3→partner) and Y-score (partner→COL9A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	AICDA →	+0.056	+3.898	.001	.005	3	1
LUNG_SCLC	LCE3D →	+0.048	+3.817	.001	.004	3	1
LUNG_SCLC	KRTAP4-12 →	+0.030	+4.169	<.001	.001	3	1
LUNG_SCLC	CT45A9 →	+0.688	+4.256	<.001	.002	3	1
LUNG_NSCLC_LUSC	MC3R →	+0.446	+4.108	.009	.005	3	1
LUNG_NSCLC_LUSC	DEFB124 →	+0.187	+4.108	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

AICDA by COL9A3 expression — LUNG_SCLC

Explore this box plot interactively →