COL9A2

Across TCGA patient cohorts, COL9A2 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL9A2-associated genes across cancer lineages are ACC1, NF2, and 4E-BP1. Each is linked with COL9A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL9A2-to-partner and partner-to-COL9A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC1 grouped by COL9A2-low versus COL9A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL9A2→partner) and Y-score (partner→COL9A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.401	+3.335	.004	.005	3	2
UCEC	NF2 →	+0.223	+2.000	.008	.029	3	2
UCEC	4E-BP1 →	+0.383	+2.502	<.001	.002	3	2
SKCM	Src →	-0.242	-3.000	.043	.035	3	1
UCEC	eIF4E →	+0.177	+2.820	.032	.035	3	1
UCEC	ERK2 →	+0.173	+2.000	.021	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ACC1 by COL9A2 expression — UCEC

Explore this box plot interactively →