COL9A1

Across TCGA patient cohorts, COL9A1 mutation is significantly associated with the RNA expression of many other genes, with 5,107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL9A1-associated genes across cancer lineages are SNORD105B, CCDC137, and MYBL2. Each is linked with COL9A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL9A1-to-partner and partner-to-COL9A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD105B grouped by COL9A1-low versus COL9A1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL9A1→partner) and Y-score (partner→COL9A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SNORD105B →	+0.404	+3.874	<.001	.006	3	4
UCEC	CCDC137 →	+0.389	+1.461	<.001	<.001	3	4
LUAD	MYBL2 →	+1.068	+2.924	.001	<.001	3	4
UCEC	CDCA5 →	+0.783	+2.332	<.001	<.001	3	4
UCEC	TMUB1 →	+0.340	+1.595	<.001	<.001	3	4
UCEC	TMEM126A →	+0.393	+1.750	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,107 associations by consensus.

SNORD105B by COL9A1 expression — CESC

Explore this box plot interactively →