COL9A1

Across TCGA cell cohorts, COL9A1 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible COL9A1-associated genes across cancer lineages are MT1HL1, TAAR6, and TBATA. Each is linked with COL9A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL9A1-to-partner and partner-to-COL9A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT1HL1 grouped by COL9A1-low versus COL9A1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL9A1→partner) and Y-score (partner→COL9A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	MT1HL1 →	+0.200	+3.817	<.001	.004	3	2
PANCREAS	TAAR6 →	+0.036	+5.000	<.001	.006	3	1
CNS	TBATA →	+0.023	+6.357	<.001	<.001	3	1
BREAST	LRIT1 →	+0.014	+3.672	.002	.006	3	1
BREAST	OR10K2 →	+0.038	+4.196	<.001	.006	3	1
BREAST	OR10T2 →	+0.110	+4.196	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

MT1HL1 by COL9A1 expression — LUNG_SCLC

Explore this box plot interactively →