COL8A2

Across TCGA patient cohorts, COL8A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,757 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COL8A2-associated proteins across cancer lineages are VCAN, CTHRC1, and THBS2. Each is linked with COL8A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both COL8A2-to-partner and partner-to-COL8A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL8A2 versus VCAN in OV, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL8A2→partner) and Y-score (partner→COL8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCAN →	+1.037	+1.332	<.001	<.001	3	9
BRCA	CTHRC1 →	+0.968	+1.682	<.001	<.001	3	9
CCRCC	THBS2 →	+1.272	+0.628	<.001	.003	3	9
CCRCC	PDLIM4 →	+0.744	+0.493	<.001	.006	3	8
OV	ITGB5 →	+0.694	+1.569	<.001	<.001	3	8
BRCA	ISLR →	+0.913	+1.796	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,757 associations by consensus.

COL8A2 vs VCAN — OV

Explore this scatter interactively →