COL8A2

Across TCGA patient cohorts, COL8A2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,219 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL8A2-associated genes across cancer lineages are UACA, LGALS1, and TIMP3. Each is linked with COL8A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL8A2-to-partner and partner-to-COL8A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL8A2 versus UACA in BRCA, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL8A2→partner) and Y-score (partner→COL8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UACA →	+1.254	+0.912	<.001	.003	3	3
OV	LGALS1 →	+1.634	+1.863	<.001	<.001	3	2
BRCA	TIMP3 →	+2.142	+1.041	<.001	.006	3	2
OV	PROCR →	+1.352	+1.425	<.001	.006	3	2
BRCA	ISM1 →	+2.575	+1.132	<.001	.002	3	2
BRCA	FGF14 →	+0.488	+0.877	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,219 associations by consensus.

COL8A2 vs UACA — BRCA

Explore this scatter interactively →