COL8A2

Across TCGA patient cohorts, COL8A2 mutation is significantly associated with the RNA expression of many other genes, with 903 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible COL8A2-associated genes across cancer lineages are RBMY2QP, RNA5SP73, and DLGAP2-AS1. Each is linked with COL8A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL8A2-to-partner and partner-to-COL8A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY2QP grouped by COL8A2-low versus COL8A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL8A2→partner) and Y-score (partner→COL8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RBMY2QP →	+0.604	+2.551	.002	.001	3	2
LIHC	RNA5SP73 →	+0.558	+4.647	<.001	.007	3	2
LIHC	DLGAP2-AS1 →	+0.017	+5.676	<.001	.001	3	2
LIHC	MIR4729 →	+0.427	+4.647	<.001	.007	3	2
LIHC	MIR3163 →	+0.679	+4.451	<.001	.006	3	2
UCEC	RNU6-1155P →	+0.158	+4.890	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 903 associations by consensus.

RBMY2QP by COL8A2 expression — SKCM

Explore this box plot interactively →