COL8A1

Across TCGA patient cohorts, COL8A1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,313 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL8A1-associated genes across cancer lineages are ISLR, MSRB3, and MYL9. Each is linked with COL8A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both COL8A1-to-partner and partner-to-COL8A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL8A1 versus ISLR in OV, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL8A1→partner) and Y-score (partner→COL8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ISLR →	+1.693	+1.116	<.001	<.001	3	9
OV	MSRB3 →	+1.470	+1.294	<.001	<.001	3	9
GBM	MYL9 →	+1.525	+1.187	<.001	.001	3	8
OV	SRPX2 →	+1.382	+1.150	<.001	<.001	3	8
OV	ACTA2 →	+2.312	+1.297	<.001	<.001	3	8
OV	GLT8D2 →	+1.383	+1.099	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,313 associations by consensus.

COL8A1 vs ISLR — OV

Explore this scatter interactively →