COL8A1

Across TCGA cell cohorts, COL8A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,326 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COL8A1-associated GO terms across cancer lineages are Positive regulation of extracellular matrix organization, Positive regulation of supramolecular fiber organization, and Regulation of protein localization to mitochondrion. Each is linked with COL8A1 in more than 13 cancer types. Because this analysis shows association rather than direction, both COL8A1-to-partner and partner-to-COL8A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of extracellular matrix organization grouped by COL8A1-low versus COL8A1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL8A1→partner) and Y-score (partner→COL8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of extracellular matrix organization →	+0.199	+3.658	<.001	<.001	3	14
STOMACH	Positive regulation of supramolecular fiber organization →	+0.101	+1.390	<.001	.003	3	13
BREAST	Regulation of protein localization to mitochondrion →	+0.126	+3.012	<.001	<.001	3	13
STOMACH	Protein activation cascade →	+0.327	+2.169	<.001	.007	3	13
STOMACH	Blood coagulation, fibrin clot formation →	+0.344	+2.482	.002	.003	3	13
LIVER	Maintenance of protein location →	+0.127	+3.156	.002	.007	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,326 associations by consensus.

Positive regulation of extracellular matrix organization by COL8A1 expression — BREAST

Explore this box plot interactively →