COL7A1

Across TCGA patient cohorts, COL7A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,540 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL7A1-associated proteins across cancer lineages are P4HA2, PLAU, and CRTAP. Each is linked with COL7A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL7A1-to-partner and partner-to-COL7A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL7A1 versus P4HA2 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL7A1→partner) and Y-score (partner→COL7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P4HA2 →	+0.867	+1.325	<.001	<.001	3	7
CCRCC	PLAU →	+1.117	+2.381	.002	<.001	3	7
BRCA	CRTAP →	+0.677	+1.513	<.001	<.001	3	7
GBM	P3H3 →	+0.601	+0.920	.003	.001	3	6
BRCA	MMP14 →	+0.559	+1.337	<.001	<.001	3	6
GBM	COL5A1 →	+0.630	+0.757	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,540 associations by consensus.

COL7A1 vs P4HA2 — GBM

Explore this scatter interactively →