COL7A1

Across TCGA patient cohorts, COL7A1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,367 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COL7A1-associated genes across cancer lineages are ITGA5, CXCL8, and MET. Each is linked with COL7A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL7A1-to-partner and partner-to-COL7A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL7A1 versus ITGA5 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL7A1→partner) and Y-score (partner→COL7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGA5 →	+1.030	+0.552	.001	<.001	3	5
LUAD	CXCL8 →	+1.877	+0.534	.001	.006	2	6
UCEC	MET →	+1.055	+0.590	.008	.004	3	4
UCEC	TREM1 →	+1.095	+0.630	<.001	<.001	3	4
PDAC	POSTN →	+1.645	+0.932	<.001	<.001	3	4
COAD	IKBIP →	+0.688	+0.534	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,367 associations by consensus.

COL7A1 vs ITGA5 — GBM

Explore this scatter interactively →