COL7A1

Across TCGA patient cohorts, COL7A1 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,871 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL7A1-associated proteins across cancer lineages are COL6A3, LAMA3, and LAMB3. Each is linked with COL7A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL7A1-to-partner and partner-to-COL7A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL7A1 versus COL6A3 in GBM, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL7A1→partner) and Y-score (partner→COL7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COL6A3 →	+0.923	+0.340	<.001	<.001	3	6
OV	LAMA3 →	+1.484	+0.862	<.001	<.001	3	6
LSCC	LAMB3 →	+1.059	+0.963	<.001	<.001	3	6
BRCA	LOXL2 →	+1.076	+0.678	<.001	<.001	3	6
LSCC	BMP1 →	+0.486	+0.700	<.001	<.001	3	5
LSCC	AHNAK2_S3408 →	+1.288	+0.737	.007	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,871 associations by consensus.

COL7A1 vs COL6A3 — GBM

Explore this scatter interactively →