COL7A1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COL7A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,964 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible COL7A1-associated GO terms across cancer lineages are Collagen fibril organization, Response to acetaldehyde, and Cellular response to acetaldehyde. Each is linked with COL7A1 in more than 14 cancer types. Because this analysis shows association rather than direction, both COL7A1-to-partner and partner-to-COL7A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by COL7A1-low versus COL7A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL7A1→partner) and Y-score (partner→COL7A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONECollagen fibril organization →+0.362+2.920.002<.001315
SOFT_TISSUEResponse to acetaldehyde →+0.263+1.809.001<.001313
SOFT_TISSUECellular response to acetaldehyde →+0.263+1.809.001<.001313
LIVEREndodermal cell differentiation →+0.186+3.545.008<.001214
KIDNEYGlial cell migration →+0.147+1.894.003.002311
KIDNEYMorphogenesis of an epithelial sheet →+0.153+2.192.006.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,964 associations by consensus.

Collagen fibril organization by COL7A1 expression — BONE

Box plot of Collagen fibril organization in COL7A1-low vs COL7A1-high samples in BONE.

Explore this box plot interactively →

Exploration