Across TCGA patient cohorts, COL6A6 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,107 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL6A6-associated proteins across cancer lineages are PPP1R18, TLN1, and TMEM119. Each is linked with COL6A6 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL6A6-to-partner and partner-to-COL6A6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A6→partner) and Y-score (partner→COL6A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP1R18 →	+0.545	+0.937	<.001	<.001	3	6
UCEC	TLN1 →	+0.611	+0.674	<.001	<.001	3	6
UCEC	TMEM119 →	+0.759	+0.521	<.001	.003	3	6
UCEC	QKI →	+0.256	+0.450	.001	.001	3	6
OV	PECAM1 →	+0.501	+0.955	<.001	<.001	3	6
OV	PIP4K2A →	+0.485	+0.896	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,107 associations by consensus.

Exploration

COL6A6 survival (RNA) · tumor vs normal (RNA) · all COL6A6 data types