COL6A3

Across TCGA patient cohorts, COL6A3 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,036 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL6A3-associated proteins across cancer lineages are THBS2, P3H1, and PCOLCE. Each is linked with COL6A3 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL6A3-to-partner and partner-to-COL6A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL6A3 versus THBS2 in OV, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A3→partner) and Y-score (partner→COL6A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THBS2 →	+1.394	+1.660	<.001	<.001	3	10
GBM	P3H1 →	+0.750	+2.220	<.001	<.001	3	10
GBM	PCOLCE →	+1.064	+2.354	<.001	<.001	3	10
OV	PDGFRB →	+0.678	+1.879	<.001	<.001	3	10
BRCA	MRC2 →	+0.804	+1.851	<.001	<.001	3	10
OV	ISLR →	+0.855	+1.636	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,036 associations by consensus.

COL6A3 vs THBS2 — OV

Explore this scatter interactively →