COL6A3

Across TCGA patient cohorts, COL6A3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,949 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COL6A3-associated genes across cancer lineages are CRISPLD2, ACTA2, and CD93. Each is linked with COL6A3 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL6A3-to-partner and partner-to-COL6A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL6A3 versus CRISPLD2 in BRCA, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A3→partner) and Y-score (partner→COL6A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CRISPLD2 →	+1.282	+0.765	<.001	<.001	3	10
OV	ACTA2 →	+1.845	+0.638	<.001	<.001	3	10
BRCA	CD93 →	+1.058	+0.740	<.001	<.001	3	10
BRCA	AOC3 →	+1.442	+0.720	<.001	<.001	3	10
OV	EMILIN1 →	+1.430	+0.613	<.001	<.001	3	10
BRCA	TGFB1I1 →	+1.015	+0.691	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,949 associations by consensus.

COL6A3 vs CRISPLD2 — BRCA

Explore this scatter interactively →