COL6A3

Across TCGA cell cohorts, COL6A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,575 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COL6A3-associated GO terms across cancer lineages are Connective tissue replacement involved in inflammatory response wound healing, Connective tissue replacement, and Positive regulation of cell-substrate junction organization. Each is linked with COL6A3 in more than 10 cancer types. Because this analysis shows association rather than direction, both COL6A3-to-partner and partner-to-COL6A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Connective tissue replacement involved in inflammatory response wound healing grouped by COL6A3-low versus COL6A3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL6A3→partner) and Y-score (partner→COL6A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Connective tissue replacement involved in inflammatory response wound healing →	+0.201	+1.265	<.001	.004	3	11
LUNG_NSCLC_LUAD	Connective tissue replacement →	+0.201	+1.265	<.001	.004	3	11
LIVER	Positive regulation of cell-substrate junction organization →	+0.153	+5.720	<.001	.001	3	9
URINARY_TRACT	Exploration behavior →	+0.204	+1.402	.001	.003	3	9
BONE	Positive regulation of focal adhesion assembly →	+0.283	+7.417	<.001	<.001	3	9
BONE	COPII-coated vesicle cargo loading →	+0.136	+5.410	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,575 associations by consensus.

Connective tissue replacement involved in inflammatory response wound healing by COL6A3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →