Across TCGA patient cohorts, COL5A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,527 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL5A2-associated proteins across cancer lineages are THBS2, PLS3, and PXDN. Each is linked with COL5A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL5A2-to-partner and partner-to-COL5A2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL5A2→partner) and Y-score (partner→COL5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THBS2 →	+1.560	+2.090	<.001	<.001	3	10
OV	PLS3 →	+0.948	+1.807	<.001	<.001	3	10
CCRCC	PXDN →	+0.618	+0.746	<.001	<.001	3	10
OV	C1R →	+0.742	+1.919	<.001	<.001	3	10
UCEC	CALD1 →	+1.156	+0.897	<.001	<.001	3	10
OV	CCDC80 →	+1.122	+2.256	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,527 associations by consensus.

Exploration

COL5A2 survival (RNA) · tumor vs normal (RNA) · all COL5A2 data types