Across TCGA patient cohorts, COL5A2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,296 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL5A2-associated genes across cancer lineages are COL1A1, LAMA4, and SPARC. Each is linked with COL5A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL5A2-to-partner and partner-to-COL5A2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL5A2→partner) and Y-score (partner→COL5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL1A1 →	+2.738	+0.826	<.001	<.001	3	10
OV	LAMA4 →	+1.242	+0.766	<.001	<.001	3	10
BRCA	SPARC →	+1.765	+1.049	<.001	<.001	3	10
OV	PDGFRB →	+1.729	+0.797	<.001	<.001	3	10
OV	COL5A1 →	+2.163	+0.742	<.001	<.001	3	10
OV	COL6A2 →	+1.835	+0.718	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,296 associations by consensus.

Exploration

COL5A2 survival (RNA) · tumor vs normal (RNA) · all COL5A2 data types