COL5A1

Across TCGA patient cohorts, COL5A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,877 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL5A1-associated proteins across cancer lineages are RARRES2, POSTN, and PCOLCE. Each is linked with COL5A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL5A1-to-partner and partner-to-COL5A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL5A1 versus RARRES2 in PDAC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL5A1→partner) and Y-score (partner→COL5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RARRES2 →	+0.813	+1.015	<.001	<.001	3	10
GBM	POSTN →	+1.421	+1.614	<.001	<.001	3	10
CCRCC	PCOLCE →	+0.917	+1.669	<.001	<.001	3	10
BRCA	MRC2 →	+0.772	+1.749	<.001	<.001	3	10
GBM	RCN3 →	+0.818	+1.657	<.001	<.001	3	10
OV	SEC23A →	+0.401	+1.848	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,877 associations by consensus.

COL5A1 vs RARRES2 — PDAC

Explore this scatter interactively →