Across TCGA patient cohorts, COL4A5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,839 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL4A5-associated proteins across cancer lineages are CLSTN1, ARHGEF10L, and FRMD6_S544. Each is linked with COL4A5 in more than 4 cancer types. Because this analysis shows association rather than direction, both COL4A5-to-partner and partner-to-COL4A5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A5→partner) and Y-score (partner→COL4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CLSTN1 →	+0.602	+1.556	<.001	<.001	3	5
BRCA	ARHGEF10L →	-0.423	-1.427	<.001	<.001	3	4
LSCC	FRMD6_S544 →	+0.730	+1.319	.005	<.001	3	4
HNSC	GLCCI1_S398 →	-0.560	-1.240	.001	.004	3	4
OV	SH3PXD2B →	+0.449	+0.912	<.001	.001	3	4
OV	SPARC →	+0.619	+0.918	.007	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,839 associations by consensus.

Exploration

COL4A5 survival (RNA) · tumor vs normal (RNA) · all COL4A5 data types