Across TCGA patient cohorts, COL4A5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,937 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COL4A5-associated genes across cancer lineages are RPL5P8, COL4A6, and RPL23AP95. Each is linked with COL4A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL4A5-to-partner and partner-to-COL4A5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A5→partner) and Y-score (partner→COL4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL5P8 →	+1.426	+1.837	<.001	.004	3	2
HNSC	COL4A6 →	+1.217	+0.570	.006	.005	3	2
LSCC	RPL23AP95 →	-0.631	-0.639	.003	.002	3	2
BRCA	KRT6B →	+4.425	+1.068	<.001	<.001	3	2
CCRCC	ATP6V1D →	+0.453	+0.589	<.001	.006	3	1
CCRCC	TIMM9 →	+0.385	+0.524	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,937 associations by consensus.

Exploration

COL4A5 survival (RNA) · tumor vs normal (RNA) · all COL4A5 data types