Across TCGA cell cohorts, COL4A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,430 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COL4A5-associated GO terms across cancer lineages are Positive regulation of purine nucleotide biosynthetic process, Negative regulation of p38MAPK cascade, and Positive regulation of nucleotide biosynthetic process. Each is linked with COL4A5 in more than 8 cancer types. Because this analysis shows association rather than direction, both COL4A5-to-partner and partner-to-COL4A5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A5→partner) and Y-score (partner→COL4A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of purine nucleotide biosynthetic process →	+0.110	+1.563	.001	.008	3	9
BREAST	Negative regulation of p38MAPK cascade →	+0.132	+1.471	<.001	.001	3	9
BREAST	Positive regulation of nucleotide biosynthetic process →	+0.110	+1.563	.001	.008	3	9
PANCREAS	Regulation of intracellular protein transport →	+0.056	+2.630	.002	<.001	3	9
SKIN	Positive regulation of hippo signaling →	+0.091	+1.988	<.001	<.001	3	9
SKIN	Cellular response to environmental stimulus →	+0.038	+2.065	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,430 associations by consensus.

Exploration

COL4A5 survival (RNA) · tumor vs normal (RNA) · all COL4A5 data types