COL4A2

Across TCGA cell cohorts, COL4A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,698 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible COL4A2-associated GO terms across cancer lineages are Collagen fibril organization, Extracellular matrix organization, and Extracellular structure organization. Each is linked with COL4A2 in more than 12 cancer types. Because this analysis shows association rather than direction, both COL4A2-to-partner and partner-to-COL4A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by COL4A2-low versus COL4A2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL4A2→partner) and Y-score (partner→COL4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Collagen fibril organization →	+0.376	+5.666	<.001	<.001	3	13
CNS	Extracellular matrix organization →	+0.128	+2.250	<.001	<.001	3	11
CNS	Extracellular structure organization →	+0.128	+2.250	<.001	<.001	3	11
SOFT_TISSUE	Substrate adhesion-dependent cell spreading →	+0.161	+3.181	<.001	<.001	3	10
KIDNEY	Wound healing →	+0.119	+2.670	<.001	.007	2	11
BREAST	Apoptotic cell clearance →	+0.158	+2.422	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,698 associations by consensus.

Collagen fibril organization by COL4A2 expression — LIVER

Explore this box plot interactively →