COL3A1

Across TCGA cell cohorts, COL3A1 mutation is significantly associated with the RNA expression of many other genes, with 501 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL3A1-associated genes across cancer lineages are CD164L2, SLC11A1, and CXorf51A. Each is linked with COL3A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL3A1-to-partner and partner-to-COL3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD164L2 grouped by COL3A1-low versus COL3A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL3A1→partner) and Y-score (partner→COL3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD164L2 →	+0.453	+3.350	.005	.001	3	3
LUNG_NSCLC_LUAD	SLC11A1 →	+0.299	+2.621	.003	.003	3	2
LUNG_NSCLC_LUAD	CXorf51A →	+0.028	+2.565	<.001	.002	3	2
LUNG_NSCLC_LUAD	RFPL4AL1 →	+0.135	+2.729	<.001	.005	3	2
SKIN	NRCAM →	-1.840	-3.254	.003	.003	3	2
UPPER_AERODIGESTIVE_TRACT	MTRNR2L10 →	+0.151	+4.209	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 501 associations by consensus.

CD164L2 by COL3A1 expression — LARGE_INTESTINE

Explore this box plot interactively →