COL28A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL28A1 mutation is significantly associated with the RNA expression of many other genes, with 3,247 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL28A1-associated genes across cancer lineages are TBR1, RNU7-127P, and RN7SL510P. Each is linked with COL28A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL28A1-to-partner and partner-to-COL28A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL28A1→partner) and Y-score (partner→COL28A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADTBR1 →+0.232+3.195<.001.00333
LUADRNU7-127P →+0.269+2.975<.001.00933
LUADRN7SL510P →+0.237+2.516.005.00533
UCECTLE6 →+0.683+1.828<.001<.00133
UCECPACRG →-1.027-2.050<.001<.00133
UCECGTF3A →+0.344+2.364<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,247 associations by consensus.

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