Across TCGA patient cohorts, COL27A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,009 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL27A1-associated proteins across cancer lineages are WIZ, HID1, and SEC23B. Each is linked with COL27A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both COL27A1-to-partner and partner-to-COL27A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL27A1→partner) and Y-score (partner→COL27A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WIZ →	+0.246	+1.351	.001	<.001	3	5
BRCA	HID1 →	-0.827	-1.445	<.001	<.001	3	4
OV	SEC23B →	-0.305	-1.283	<.001	<.001	3	4
HNSC	EGFR →	+0.955	+0.986	<.001	<.001	3	4
GBM	VAV2 →	+0.383	+0.620	.001	.007	2	4
GBM	MLYCD →	-0.331	-0.898	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,009 associations by consensus.

Exploration

COL27A1 survival (RNA) · tumor vs normal (RNA) · all COL27A1 data types