Across TCGA patient cohorts, COL25A1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,056 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL25A1-associated proteins across cancer lineages are ATF1_S198, ATXN2L_S634, and BIRC6_S449. Each is linked with COL25A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL25A1-to-partner and partner-to-COL25A1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL25A1→partner) and Y-score (partner→COL25A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ATF1_S198 →	-0.537	-0.757	.001	.002	3	1
GBM	ATXN2L_S634 →	-1.303	-1.056	<.001	.004	3	1
GBM	BIRC6_S449 →	-1.114	-0.958	<.001	.003	3	1
GBM	BMP7 →	+0.858	+1.033	.003	.001	3	1
GBM	BPTF_S2465 →	-1.226	-0.973	<.001	.001	3	1
GBM	ADAM9_S799 →	-0.683	-0.893	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,056 associations by consensus.

Exploration

COL25A1 survival (RNA) · tumor vs normal (RNA) · all COL25A1 data types