COL24A1

Across TCGA patient cohorts, COL24A1 mutation is significantly associated with the RNA expression of many other genes, with 8,516 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL24A1-associated genes across cancer lineages are PYCR1, CEP76, and GPR3. Each is linked with COL24A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL24A1-to-partner and partner-to-COL24A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYCR1 grouped by COL24A1-low versus COL24A1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL24A1→partner) and Y-score (partner→COL24A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	PYCR1 →	+1.008	+3.331	.003	.005	2	6
HNSC	CEP76 →	+0.629	+3.494	<.001	.002	3	5
SKCM	GPR3 →	+0.450	+1.756	.006	.003	3	5
UCEC	EIF1AD →	+0.378	+2.438	<.001	<.001	3	5
UCEC	NDC80 →	+0.631	+2.053	<.001	<.001	3	5
CESC	BCL7A →	+0.802	+3.371	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,516 associations by consensus.

PYCR1 by COL24A1 expression — CESC

Explore this box plot interactively →