COL24A1

Across TCGA patient cohorts, COL24A1 mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL24A1-associated genes across cancer lineages are Cyclin-B1, ASNS, and TIGAR. Each is linked with COL24A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both COL24A1-to-partner and partner-to-COL24A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by COL24A1-low versus COL24A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL24A1→partner) and Y-score (partner→COL24A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.627	+1.502	<.001	<.001	3	5
STAD	ASNS →	+0.428	+2.321	.032	.034	3	4
LUSC	TIGAR →	+0.224	+1.746	<.001	.024	3	3
LUAD	4E-BP1 →	+0.310	+2.222	.009	.010	3	3
UCEC	FASN →	+0.212	+1.289	.043	.021	3	3
UCEC	INPP4B →	-0.220	-1.938	.010	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Cyclin-B1 by COL24A1 expression — UCEC

Explore this box plot interactively →