COL24A1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COL24A1 mutation is significantly associated with the RNA expression of many other genes, with 454 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL24A1-associated genes across cancer lineages are PNMA6F, GAGE10, and USP17L17. Each is linked with COL24A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL24A1-to-partner and partner-to-COL24A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNMA6F grouped by COL24A1-low versus COL24A1-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL24A1→partner) and Y-score (partner→COL24A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYPNMA6F →+0.006+5.000<.001.00532
BLOOD_LeukemiaGAGE10 →+0.080+3.187<.001.00132
BLOOD_LeukemiaUSP17L17 →+0.002+3.984<.001.00632
LUNG_NSCLC_LUADRASA4 →-1.153-3.099.001.00832
LUNG_NSCLC_LUADSLAMF9 →-0.385-3.447.009<.00132
LARGE_INTESTINETNRC6B →+0.597+3.386.006.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 454 associations by consensus.

PNMA6F by COL24A1 expression — KIDNEY

Box plot of PNMA6F in COL24A1-low vs COL24A1-high samples in KIDNEY.

Explore this box plot interactively →

Exploration