COL23A1

Across TCGA cell cohorts, COL23A1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COL23A1-associated genes across cancer lineages are PRR27, TNP1, and RLN3. Each is linked with COL23A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL23A1-to-partner and partner-to-COL23A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR27 grouped by COL23A1-low versus COL23A1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL23A1→partner) and Y-score (partner→COL23A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRR27 →	+0.023	+5.614	<.001	.002	3	1
SOFT_TISSUE	TNP1 →	+1.481	+5.369	<.001	.004	3	1
SOFT_TISSUE	RLN3 →	+0.041	+5.369	<.001	.004	3	1
SKIN	ART4 →	+0.184	+3.556	<.001	.007	3	1
SKIN	SLC7A14 →	+0.572	+3.772	<.001	.003	3	1
SKIN	SPHKAP →	+0.020	+3.877	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

PRR27 by COL23A1 expression — PANCREAS

Explore this box plot interactively →