COL22A1

Across TCGA patient cohorts, COL22A1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,800 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL22A1-associated genes across cancer lineages are MCHR1, LGALS1, and RENBP. Each is linked with COL22A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL22A1-to-partner and partner-to-COL22A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL22A1 versus MCHR1 in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL22A1→partner) and Y-score (partner→COL22A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCHR1 →	+1.158	+0.793	<.001	<.001	3	3
GBM	LGALS1 →	+0.854	+0.728	<.001	<.001	3	2
GBM	RENBP →	+0.681	+0.576	<.001	.006	3	2
GBM	MEDAG →	+1.138	+1.025	.006	.003	3	2
GBM	RELB →	+0.654	+0.816	.001	<.001	3	2
GBM	CCL2 →	+1.653	+0.809	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,800 associations by consensus.

COL22A1 vs MCHR1 — GBM

Explore this scatter interactively →