COL22A1

Across TCGA cell cohorts, COL22A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,611 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COL22A1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with COL22A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both COL22A1-to-partner and partner-to-COL22A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by COL22A1-low versus COL22A1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COL22A1→partner) and Y-score (partner→COL22A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.095	+3.157	.003	<.001	2	9
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+2.404	<.001	.001	2	9
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.093	+2.578	.002	.004	3	8
SKIN	Viral process →	+0.058	+1.923	.002	.003	3	8
BLOOD_Lymphoma	Positive regulation of ATP-dependent activity →	+0.057	+0.700	.007	.007	2	8
BLOOD_Lymphoma	Endosome organization →	+0.028	+1.044	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,611 associations by consensus.

Regulation of myoblast fusion by COL22A1 expression — LUNG_SCLC

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