COL21A1

Across TCGA patient cohorts, COL21A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,879 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COL21A1-associated proteins across cancer lineages are CAVIN1, CRIP2, and DEPTOR. Each is linked with COL21A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL21A1-to-partner and partner-to-COL21A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL21A1 versus CAVIN1 in BRCA, with a Pearson correlation of 0.21.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL21A1→partner) and Y-score (partner→COL21A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CAVIN1 →	+0.633	+0.605	<.001	.003	3	6
LSCC	CRIP2 →	+0.430	+1.082	<.001	<.001	3	6
GBM	DEPTOR →	+0.519	+1.082	<.001	<.001	3	6
LSCC	DNAJC7 →	-0.327	-1.469	<.001	<.001	3	6
CCRCC	MAMDC2 →	+0.602	+1.367	.004	<.001	3	6
LUAD	DCLK1 →	+0.734	+1.327	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,879 associations by consensus.

COL21A1 vs CAVIN1 — BRCA

Explore this scatter interactively →