COL20A1

Across TCGA pan-cancer cohorts, COL20A1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated COL20A1 data layer compared with 29 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher COL20A1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated COL20A1 expression acts as an unfavorable survival marker.

BRCA, HNSC, and LUSC are the cancer types where COL20A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.721	0.964	<.001	46	view →
HNSC	DFS	Median	IV	0.089	0.645	<.001	33	view →
LUSC	OS	Median	II,III,IV	0.412	0.744	.003	9	view →
GBM	OS	Median	All	0.075	0.413	.003	6	view →
ACC	OS	Median	All	0.250	0.642	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

COL20A1–BRCA (OS)

Open the BRCA breakdown →