COL20A1

Across TCGA patient cohorts, COL20A1 mutation is significantly associated with the RNA expression of many other genes, with 5,399 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL20A1-associated genes across cancer lineages are WDHD1, CHEK1, and SKA1. Each is linked with COL20A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL20A1-to-partner and partner-to-COL20A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDHD1 grouped by COL20A1-low versus COL20A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL20A1→partner) and Y-score (partner→COL20A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDHD1 →	+0.671	+2.684	<.001	<.001	3	4
UCEC	CHEK1 →	+0.561	+1.869	<.001	.004	3	4
UCEC	SKA1 →	+0.637	+1.868	<.001	<.001	3	4
UCEC	PBK →	+0.737	+1.868	<.001	<.001	3	4
UCEC	MCM10 →	+0.641	+1.898	<.001	.001	3	4
UCEC	PRR34-AS1 →	+0.572	+2.513	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,399 associations by consensus.

WDHD1 by COL20A1 expression — UCEC

Explore this box plot interactively →