COL1A1

Across TCGA patient cohorts, COL1A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,164 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL1A1-associated proteins across cancer lineages are SRPX2, SULF1, and THBS2. Each is linked with COL1A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL1A1-to-partner and partner-to-COL1A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL1A1 versus SRPX2 in CCRCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL1A1→partner) and Y-score (partner→COL1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SRPX2 →	+0.962	+1.605	<.001	<.001	3	10
OV	SULF1 →	+0.898	+2.760	<.001	<.001	3	10
CCRCC	THBS2 →	+1.475	+1.874	<.001	<.001	3	10
CCRCC	PCOLCE →	+0.941	+2.088	<.001	<.001	3	10
GBM	MMP14 →	+0.623	+2.361	<.001	<.001	3	10
BRCA	MRC2 →	+0.741	+1.944	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,164 associations by consensus.

COL1A1 vs SRPX2 — CCRCC

Explore this scatter interactively →