COL19A1

Across TCGA patient cohorts, COL19A1 mutation is significantly associated with the total protein of many other genes, with 82 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL19A1-associated genes across cancer lineages are ASNS, PCNA, and p38-MAPK_pT180_Y182. Each is linked with COL19A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL19A1-to-partner and partner-to-COL19A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by COL19A1-low versus COL19A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL19A1→partner) and Y-score (partner→COL19A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.383	+1.432	<.001	.004	3	4
LUSC	PCNA →	+0.167	+1.371	.014	.022	3	3
LUAD	p38-MAPK_pT180_Y182 →	-0.284	-2.115	.013	.015	3	3
LUAD	S6_pS235_S236 →	-0.393	-1.807	.004	.004	3	3
LUAD	S6_pS240_S244 →	-0.436	-1.906	.007	.014	3	3
LUAD	STAT3_pY705 →	-0.225	-1.514	.010	.014	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

ASNS by COL19A1 expression — UCEC

Explore this box plot interactively →