COL19A1

Across TCGA cell cohorts, COL19A1 mutation is significantly associated with the RNA expression of many other genes, with 505 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL19A1-associated genes across cancer lineages are LCE6A, OR6F1, and FIGLA. Each is linked with COL19A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL19A1-to-partner and partner-to-COL19A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE6A grouped by COL19A1-low versus COL19A1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL19A1→partner) and Y-score (partner→COL19A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LCE6A →	+0.040	+5.977	<.001	.001	3	2
BREAST	OR6F1 →	+0.051	+3.251	<.001	.002	3	2
LUNG_SCLC	FIGLA →	+0.109	+2.459	<.001	.006	3	2
BREAST	NPSR1 →	+0.039	+3.228	<.001	.003	3	2
SKIN	LAMTOR3 →	+0.418	+2.067	.001	.004	3	2
SKIN	TP53TG5 →	-0.211	-1.777	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 505 associations by consensus.

LCE6A by COL19A1 expression — SOFT_TISSUE

Explore this box plot interactively →