Across TCGA patient cohorts, COL18A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,460 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL18A1-associated proteins across cancer lineages are COL1A1, PCOLCE, and COL12A1. Each is linked with COL18A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both COL18A1-to-partner and partner-to-COL18A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL18A1→partner) and Y-score (partner→COL18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COL1A1 →	+1.056	+0.709	<.001	<.001	3	7
BRCA	PCOLCE →	+0.845	+1.262	<.001	<.001	3	7
GBM	COL12A1 →	+0.907	+0.778	<.001	<.001	3	6
GBM	COL1A2 →	+0.959	+0.797	<.001	<.001	3	6
BRCA	COL5A2 →	+1.003	+1.097	<.001	<.001	3	6
COAD	FAP →	+0.820	+1.286	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,460 associations by consensus.

Exploration

COL18A1 survival (RNA) · tumor vs normal (RNA) · all COL18A1 data types