Across TCGA cell cohorts, COL18A1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,752 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible COL18A1-associated genes across cancer lineages are KIRREL1, AGRN, and MFGE8. Each is linked with COL18A1 in more than 10 cancer types. Because this analysis shows association rather than direction, both COL18A1-to-partner and partner-to-COL18A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL18A1→partner) and Y-score (partner→COL18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	KIRREL1 →	+2.959	+3.022	<.001	<.001	3	11
OESOPHAGUS	AGRN →	+1.969	+1.772	<.001	.002	3	10
URINARY_TRACT	MFGE8 →	+2.932	+3.761	<.001	<.001	3	10
URINARY_TRACT	COL6A1 →	+3.254	+3.172	<.001	<.001	3	10
CNS	COL6A2 →	+4.470	+2.564	<.001	<.001	3	9
BONE	PRSS23 →	+3.936	+2.336	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,752 associations by consensus.

Exploration

COL18A1 survival (RNA) · tumor vs normal (RNA) · all COL18A1 data types