Across TCGA cell cohorts, COL18A1 mutation is significantly associated with the RNA expression of many other genes, with 390 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL18A1-associated genes across cancer lineages are RAB13, IRAK1BP1, and MAP1LC3C. Each is linked with COL18A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL18A1-to-partner and partner-to-COL18A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL18A1→partner) and Y-score (partner→COL18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RAB13 →	+0.567	+2.459	<.001	.003	3	3
LARGE_INTESTINE	IRAK1BP1 →	+0.522	+2.700	<.001	.001	3	3
BLOOD_Myeloma	MAP1LC3C →	+0.041	+3.714	<.001	.002	3	2
SOFT_TISSUE	IFNW1 →	+0.012	+4.930	.003	.008	3	2
CNS	BPIFB6 →	+0.029	+4.169	<.001	.008	3	2
LARGE_INTESTINE	CBY1 →	+0.466	+1.622	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

Exploration

COL18A1 survival (RNA) · tumor vs normal (RNA) · all COL18A1 data types