COL16A1

Across TCGA pan-cancer cohorts, COL16A1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated COL16A1 data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher COL16A1 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated COL16A1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, COAD, and DLBC are the cancer types where COL16A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.970	0.861	.017	28	view →
COAD	OS	Median	IV	0.056	0.659	<.001	27	view →
DLBC	OS	Median	All	0.054	0.842	<.001	6	view →
CESC	DFS	Median	II,III,IV	0.209	0.711	.008	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	OS	Median	All	0.775	0.880	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

COL16A1–UCEC (OS)

Open the UCEC breakdown →