COL16A1

Across TCGA patient cohorts, COL16A1 mutation is significantly associated with the RNA expression of many other genes, with 3,349 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL16A1-associated genes across cancer lineages are MND1, GOT2, and UHRF1. Each is linked with COL16A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both COL16A1-to-partner and partner-to-COL16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MND1 grouped by COL16A1-low versus COL16A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL16A1→partner) and Y-score (partner→COL16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MND1 →	+0.563	+1.963	<.001	<.001	3	5
LIHC	GOT2 →	+0.617	+3.233	.006	.008	2	5
UCEC	UHRF1 →	+0.742	+1.635	<.001	<.001	3	4
UCEC	CENPM →	+0.372	+1.936	.007	.002	3	4
UCEC	FANCI →	+0.453	+1.490	<.001	<.001	3	4
UCEC	FAM43B →	-0.647	-2.152	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,349 associations by consensus.

MND1 by COL16A1 expression — UCEC

Explore this box plot interactively →