COL16A1

Across TCGA patient cohorts, COL16A1 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL16A1-associated genes across cancer lineages are PCNA, c-Met_pY1235, and TFRC. Each is linked with COL16A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL16A1-to-partner and partner-to-COL16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by COL16A1-low versus COL16A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL16A1→partner) and Y-score (partner→COL16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PCNA →	+0.260	+3.169	.006	.018	3	3
COAD	c-Met_pY1235 →	+0.117	+2.321	.007	.033	3	3
UCEC	TFRC →	+0.370	+1.369	.011	.003	3	3
BLCA	AMPK_pT172 →	-0.397	-3.169	.039	.019	3	2
COAD	eIF4E →	+0.165	+2.820	.033	.035	2	3
COAD	RAD51 →	+0.157	+2.467	.021	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

PCNA by COL16A1 expression — SKCM

Explore this box plot interactively →