COL16A1

Across TCGA cell cohorts, COL16A1 mutation is significantly associated with the RNA expression of many other genes, with 476 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL16A1-associated genes across cancer lineages are CPXCR1, S100G, and ACBD5. Each is linked with COL16A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL16A1-to-partner and partner-to-COL16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPXCR1 grouped by COL16A1-low versus COL16A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL16A1→partner) and Y-score (partner→COL16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CPXCR1 →	+0.202	+3.169	<.001	.002	2	3
OVARY	S100G →	+0.407	+3.095	<.001	.009	3	2
LARGE_INTESTINE	ACBD5 →	+0.957	+3.743	<.001	<.001	3	2
LARGE_INTESTINE	GPR63 →	+0.982	+3.743	<.001	<.001	3	2
LARGE_INTESTINE	KDSR →	+0.753	+2.628	<.001	.002	3	2
LARGE_INTESTINE	TTI2 →	+0.541	+2.628	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 476 associations by consensus.

CPXCR1 by COL16A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →